Over time, the body loses its ability to retain water. This lost moisture leads to an aged appearance or volume loss, which is the main cause of wrinkles, fine lines and sagging skin. External factors such as stress and sun exposure can also contribute to volume loss. Volume loss is the main cause of wrinkles, fine lines and sagging skin. By Injecting HA dermal fillers into the skin you can smooth, plump and lift the skin, creating a more youthful appearance.